What is mesothelioma?

Is a natural silicate mineral asbestos with people because of the combination does not transmit heat started in the old ages. On the ninth hundred years in the second half of the next industrial revolution, heat, electricity, friction, and is resistant to acid because many businesses are using the "magic mineral" as is the twentieth in the face of the second half after being karsinojenik emerged, the name "deadly dust" has been.

Asbestos as a solid physical structure (amphibol) and curve-fiber (chrysotile) has two types. Amphibol of asbestos, according to chemical structure, crocidolite (blue asbestos), amosite (brown asbestos), tremolit to anthophollite and actinolite varieties are available. Industries most frequently used in chrysotile, crocidolite and amosite were denominated. These are the most dangerous for health and crocidolite were banned in many countries using amosite'nin. 90% of the asbestos industry in many countries, including chrysotile, but is prohibited in some countries is less controversial karsinojenisitesi are used under strict control.

Asbestos disease can only enters the body through breathing. Caused diseases, may be benign or malignant. In the first group, plevrada fibrosis, calcification, effüzyon; parankima in lung fibrosis (asbestosis) is located. In the second group, the malignant mezotelyomaları pleura and peritoneum, lung cancer and even if less is available larenks and cancer of the digestive organs. No non-smoker and non-industrial relations risk of lung cancer in people 1 is approved, this rate 45'e who smokes 20 a day, and smoking, but also the 92 times out who is breathing asbestos dust. With smoking and asbestos are carcinogenic for human health when minerals can be very dangerous. In Turkey, smoking rates of men in rural areas and find the% 70'lerin however breathing asbestos fibers that have the higher our people would say the chances of cancer, you'll catch.

To make a benign or beneficial owner of the asbestos diseases, has been left to take a period of 20-40. People asbestos, work environment (vocational or occupational) or environmental (environmental or Domestic) way to breathe. Az da olsa, asbestos workers who have stuck to the powder of the clothes at home that relatives can breathe it in as indirek directly or to the left is called asbestos paraoccupational way.

In Central Anatolia in Turkey approximately 16 million people living in the rural areas are considered to have. These are approximately 25% of asbestos depends on over the age of twenty Plevral disease are benign. This ratio as a linear increase as the years progress, and can reach the 80's%. Asbestos is also mezotelyoma it is aklamMaliğn. In the Western world mezotelyoma incidence of malignant 1-2.2 / 1,000,000 / year in Turkey, while at least 500 persons per year are seen in this disease. Western countries have retired asbestos worker malignant disease mezotelyoma, our country is in middle age disease. We the people of our rural areas, environmental asbestos-Domestic way to breathe. Reported above, the most number of years it could happen by the left vocational asbestos. That is, vocational disease of the western world, our environment is our disease. Central Anatolian origin is actually working in Europe to receive compensation for their workers per mezotelyomaya shot was caught when the asbestos that accept and lungs were found in the Anatolian territories show that the request can not be accepted as tremolit. Asbestos-related diseases in workers in Europe, "Imported asbestos" and running a shameful situation, it is funny.

Turkey is working in the same confusion that is. Asbestos is processed in a factory work related illness occurs employer-worker is the problem. Asbestos workers to patients has come from his village, or did you work?

In Turkey to the left of asbestos fibers, asbestos in the white ground, "Ak soil," the heavens earth "," Ceren earth "" Çelpek "with various names, lime, plaster, roof and ground floor is used as is. Used for this purpose in the villages of Anatolia, most of the land in the industrial value of any non-asbestos tremolit have to. This type of asbestos fiber, just like blue and brown asbestos thin or thick can be long.

Asbestos, environmental way our country is connected to the left peak of disease in the region: Mihallıççik districts and villages of Eskişehir and Konya Ereğli'sinin Ayrancı Halkapınar and villages, of Çankırı Ilgaz and Şabanözü Sorgun village and district of Yozgat and villages, and Yıldızeli of Sivas Şarkışla villages, west of Diyarbakir in South Eastern Anatolia region Ergani and villages, Polu Mine and villages of Elazığ, Malatya, Adiyaman and Urfa district includes the Siverek. Coast of the Black Sea and Eastern Anatolia regions in residential areas do not have asbestos-related diseases. Connected to the asbestos left several villages in Thrace Plevral benign changes are found. Only in the villages in the Aegean region Denizli'in Tavas County, Burdur's Yeşilova region, and the Gediz Aslanapa district of Kütahya, Afyon district's Elmadag about asbestos disease was found sporadically in the villages. Mediterranean region, the slope of the Taurus Mountains in the villages and some villages of Hatay Kirikhan and Reyhanlı soil drink the above mentioned tremolit way asbestos is used by the left end of the air within the environment to develop diseases related asbesle.

The 30 species of natural zeolit'lerin a aluminosilikat crystallize only in erionite and mordenite lifsel structure. The crystal structure alone is erionite'in epidemiological lifsel, in vivo and in vitro has been shown to be as karsinojenik and fibrojenik. So far, the most potent carcinogen known Erionite'nin a mineral that is connected to the World Health Organization, the International Cancer Research Agency (International Agency for Research on Cancer) has been adopted by.

Thousands of years ago, Erciyes, Hasandağı and the volcanic lava of nearby mountains covered Melendiz that foreigners Cappadocia, Goreme said we are in the unique natural wonders of the geological structure has emerged. The region's only three-place, water and salt into the reaction of volcanic lava chabazite, clinopitololite create and crystallize as lifsel structure where erionite'nin Karain, Sarıhıdır villages and is located Tuzköy. To all of the diseases of asbestos Erionite'nin caused Göreme region has to face the day with work. This area is separate from the three villages in the other villages is infrequent, and peritoneal malignant Plevral has been shown by us to be mezotelyoma endemisi. The average age of patients from the region mezotelyomalı most people 50 and 26, were the oldest is 75. In both men and women and Disease was seen. Interesting side of the business, the disease was seen in a way more intense in some families. A family with the lymphoma mezotelyoma Plevral and peritoneal, liver cancer, bone sarcoma, tumors such as non-mezotelyoma were seen. On these observations formed the basis of cancer, although genetic predisposition factors erionite also suggests additional factors may be as effective.

Göremenin Karain, Tuzköy and the proportional mortality studies Sarıhıdır villages, the first of two who died in a village in the fact that 70% died from malignant disease has been revealed. However Kızırmağın the oldest settlements in the south of the river flooding and falling rocks in the back of people and animals by causing loss of time due to the government in 1958 villages of the north side of the river in the brick, briquette made with materials such as new home has to be moved. Be below 50% of Sarıhıdır'daki mortality rate is probably related. All patients except one in this village was born in the old villages were individuals. This event Göreme'deki the problem of cancer, but show the villages can be solved through a change of location.

Cancer Göreme'deki people in villages, houses and garden walls of the building blocks that slide into the water to breathe in erionit'ten. Bronchi of the patient and provide sekresyonunda, breathing the air in the house and in the lungs is similar to the erionite fibers and asbestos cisimcik shows zeolite cisimcik. Today only 35 digits of a village that has become a large part Karainliler'ın, for various reasons, domestic and foreign locations to maintain life. After finishing elementary school, even separated from the village who goes to the world, wherever you are mezotelyoma risk.


Mesothelioma Treatment Methods
1. İmmünoterapi and / or combination chemotherapy
Ex: + IFN-a combination of cisplatin,
cisplatin + mitomisin - C + IFN-a combination,
IL-2 or IFN-g intrakaviter,
intralezyoner GM-CSF infusion,

2. Photodynamic therapy

3. Gene therapy

4. Selective receptors for growth or antagonistic treatment faktöıü

5. Plörektomi / intrakaviter chemotherapy / postoperative chemotherapy / radiotherapy preventif

Median 4-12 months after diagnosis MPM'de between sağkalım are reported.

At the moment not possible to talk about curing the disease is below 5% in five years of life.

Treatment cases are reported with long-lived.

Prognostic factors in the life time is effective.

Can not be used in response to PA lung graph treatment.

For phase MPM'de "International mesothelioma Interest Group" (IMIG) prepared by the phase recommended for use (Table 4).

For less than the number of Olgu treatment is difficult to comment about. Studies suggest that at least 15 patients are. This case centered on the work should come into question.